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Combined Effect of Bortezomib and Menadione Sodium Bisulfite on Proteasomes of Tumor Cells: The Dramatic Decrease of Bortezomib Toxicity in a Preclinical Trial

Tumor growth is associated with elevated proteasome expression and activity. This makes proteasomes a promising target for antitumor drugs. Current antitumor drugs such as bortezomib that inhibit proteasome activity have significant side effects. The purpose of the present study was to develop effec...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cancers (Basel)
Κύριοι συγγραφείς: Astakhova, Tatiana M., Morozov, Alexey V., Erokhov, Pavel A., Mikhailovskaya, Maria I., Akopov, Sergey B., Chupikova, Natalia I., Safarov, Ruslan R., Sharova, Natalia P.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: MDPI 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209890/
https://ncbi.nlm.nih.gov/pubmed/30257462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10100351
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