Interplay Between Sub-Cellular Alterations of Calcium Release and T-Tubular Defects in Cardiac Diseases

Asynchronous Ca(2+) release promotes non-homogeneous myofilament activation, leading to mechanical dysfunction, as well as initiation of propagated calcium waves and arrhythmias. Recent advances in microscopy techniques have allowed for optical recordings of local Ca(2+) fluxes and action potentials...

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Bibliographische Detailangaben
Veröffentlicht in:Front Physiol
Hauptverfasser: Scardigli, Marina, Ferrantini, Cecilia, Crocini, Claudia, Pavone, Francesco S., Sacconi, Leonardo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209824/
https://ncbi.nlm.nih.gov/pubmed/30410446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01474
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