Suppression of miR-22, a tumor suppressor in cervical cancer, by human papillomavirus 16 E6 via a p53/miR-22/HDAC6 pathway

MicroRNAs (miRNAs) are small non-coding RNAs that function to down-regulate gene expression involving in various cellular processes related to carcinogenesis. Recently, miR-22 was identified as a tumor-suppressing miRNA in many human cancers. However, the regulatory mechanism and the specific functi...

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Udgivet i:PLoS One
Main Authors: Wongjampa, Weerayut, Ekalaksananan, Tipaya, Chopjitt, Peechanika, Chuerduangphui, Jureeporn, Kleebkaow, Pilaiwan, Patarapadungkit, Natcha, Pientong, Chamsai
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209303/
https://ncbi.nlm.nih.gov/pubmed/30379969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206644
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