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Effects of arecoline on proliferation of oral squamous cell carcinoma cells by dysregulating c-Myc and miR-22, directly targeting oncostatin M

Arecoline, the major alkaloid of areca nut, is known to induce oral carcinogenesis, however, its mechanism is still needed to elucidate. This study investigated the effects of arecoline on cell viability and cell-cycle progression of oral squamous cell carcinoma (OSCC) cells as well as a relevant ce...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Chuerduangphui, Jureeporn, Ekalaksananan, Tipaya, Chaiyarit, Ponlatham, Patarapadungkit, Natcha, Chotiyano, Apinya, Kongyingyoes, Bunkerd, Promthet, Supannee, Pientong, Chamsai
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791990/
https://ncbi.nlm.nih.gov/pubmed/29385191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192009
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