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Effects of arecoline on proliferation of oral squamous cell carcinoma cells by dysregulating c-Myc and miR-22, directly targeting oncostatin M

Arecoline, the major alkaloid of areca nut, is known to induce oral carcinogenesis, however, its mechanism is still needed to elucidate. This study investigated the effects of arecoline on cell viability and cell-cycle progression of oral squamous cell carcinoma (OSCC) cells as well as a relevant ce...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chuerduangphui, Jureeporn, Ekalaksananan, Tipaya, Chaiyarit, Ponlatham, Patarapadungkit, Natcha, Chotiyano, Apinya, Kongyingyoes, Bunkerd, Promthet, Supannee, Pientong, Chamsai
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791990/
https://ncbi.nlm.nih.gov/pubmed/29385191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192009
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