Clinical impact of intratumoral HER2 heterogeneity on trastuzumab efficacy in patients with HER2-positive gastric cancer

BACKGROUND: There is growing interest in the clinical significance of intratumoral HER2 heterogeneity. Its prognostic and predictive impacts on trastuzumab efficacy were demonstrated in breast cancer. However, its clinical significance in gastric cancer is still unclear. METHODS: Twenty-eight HER2-p...

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Detalhes bibliográficos
Publicado no:J Gastroenterol
Main Authors: Wakatsuki, Takeru, Yamamoto, Noriko, Sano, Takeshi, Chin, Keisho, Kawachi, Hiroshi, Takahari, Daisuke, Ogura, Mariko, Ichimura, Takashi, Nakayama, Izuma, Osumi, Hiroki, Matsushima, Tomohiro, Suenaga, Mitsukuni, Shinozaki, Eiji, Hiki, Naoki, Ishikawa, Yuichi, Yamaguchi, Kensei
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2018
Assuntos:
Original Article—Alimentary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209002/
https://ncbi.nlm.nih.gov/pubmed/29633013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00535-018-1464-0
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