Assessment of the direct effects of DDAH I on tumour angiogenesis in vivo

Nitric oxide (NO) has been strongly implicated in glioma progression and angiogenesis. The endogenous inhibitors of NO synthesis, asymmetric dimethylarginine (ADMA) and N-monomethyl-l-arginine (l-NMMA), are metabolized by dimethylarginine dimethylaminohydrolase (DDAH), and hence, DDAH is an intracel...

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Bibliographic Details
Published in:Angiogenesis
Main Authors: Papaevangelou, Efthymia, Boult, Jessica K. R., Whitley, Guy S., Robinson, Simon P., Howe, Franklyn A.
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2018
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208893/
https://ncbi.nlm.nih.gov/pubmed/29721731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-018-9617-6
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