Augmented liver inflammation in a microsomal prostaglandin E synthase 1 (mPGES-1)-deficient diet-induced mouse NASH model

In a subset of patients, non-alcoholic fatty liver disease (NAFLD) is complicated by cell death and inflammation resulting in non-alcoholic steatohepatitis (NASH), which may progress to fibrosis and subsequent organ failure. Apart from cytokines, prostaglandins, in particular prostaglandin E(2) (PGE...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Henkel, Janin, Coleman, Charles Dominic, Schraplau, Anne, Jöhrens, Korinna, Weiss, Thomas Siegfried, Jonas, Wenke, Schürmann, Annette, Püschel, Gerhard Paul
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208405/
https://ncbi.nlm.nih.gov/pubmed/30382148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34633-y
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