Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif

The DIR2s RNA aptamer, a second-generation, in-vitro selected binder to dimethylindole red (DIR), activates the fluorescence of cyanine dyes, DIR and oxazole thiazole blue (OTB), allowing detection of two well-resolved emission colors. Using Fab BL3-6 and its cognate hairpin as a crystallization mod...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Shelke, Sandip A., Shao, Yaming, Laski, Artur, Koirala, Deepak, Weissman, Benjamin P., Fuller, James R., Tan, Xiaohong, Constantin, Tudor P., Waggoner, Alan S., Bruchez, Marcel P., Armitage, Bruce A., Piccirilli, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208384/
https://ncbi.nlm.nih.gov/pubmed/30382099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06942-3
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados