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Twisted Cyanines: A Non-Planar Fluorogenic Dye with Superior Photostability and its Use in a Protein-Based Fluoromodule

The cyanine dye thiazole orange (TO) is a well-known fluorogenic stain for DNA and RNA, but this property precludes its use as an intracellular fluorescent probe for non-nucleic acid biomolecules. Further, as is the case with many cyanines, the dye suffers from low photostability. Here we report the...

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Detalhes bibliográficos
Main Authors: Shank, Nathaniel I., Pham, Ha, Waggoner, Alan S., Armitage, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574795/
https://ncbi.nlm.nih.gov/pubmed/23252842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja308629w
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