OKN-007 decreases free radical levels in a preclinical F98 rat glioma model

Free radicals are associated with glioma tumors. Here, we report on the ability of an anticancer nitrone compound, OKN-007 [Oklahoma Nitrone 007; a disulfonyl derivative of α-phenyl-tert-butyl nitrone (PBN)] to decrease free radical levels in F98 rat gliomas using combined molecular magnetic resonan...

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Publicado en:Free Radic Biol Med
Autores principales: de Souza, Patricia Coutinho, Smith, Nataliya, Atolagbe, Oluwatomisin, Ziegler, Jadith, Njoku, Charity, Lerner, Megan, Ehrenshaft, Marilyn, Mason, Ronald P., Meek, Bill, Plafker, Scott M., Saunders, Debra, Mamedova, Nadezda, Towner, Rheal A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208328/
https://ncbi.nlm.nih.gov/pubmed/26119786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.06.026
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