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Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): study protocol for a pilot randomized controlled trial

BACKGROUND: Trauma is the leading cause of morbidity and mortality in children in the United States. The antifibrinolytic drug tranexamic acid (TXA) improves survival in adults with traumatic hemorrhage, however, the drug has not been evaluated in a clinical trial in severely injured children. We de...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Nishijima, Daniel K., VanBuren, John, Hewes, Hilary A., Myers, Sage R., Stanley, Rachel M., Adelson, P. David, Barnhard, Sarah E., Bobinski, Matthew, Ghetti, Simona, Holmes, James F., Roberts, Ian, Schalick, Walton O., Tran, Nam K., Tzimenatos, Leah S., Michael Dean, J., Kuppermann, Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208101/
https://ncbi.nlm.nih.gov/pubmed/30376893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-018-2974-z
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