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Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): study protocol for a pilot randomized controlled trial

BACKGROUND: Trauma is the leading cause of morbidity and mortality in children in the United States. The antifibrinolytic drug tranexamic acid (TXA) improves survival in adults with traumatic hemorrhage, however, the drug has not been evaluated in a clinical trial in severely injured children. We de...

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Détails bibliographiques
Publié dans:Trials
Auteurs principaux: Nishijima, Daniel K., VanBuren, John, Hewes, Hilary A., Myers, Sage R., Stanley, Rachel M., Adelson, P. David, Barnhard, Sarah E., Bobinski, Matthew, Ghetti, Simona, Holmes, James F., Roberts, Ian, Schalick, Walton O., Tran, Nam K., Tzimenatos, Leah S., Michael Dean, J., Kuppermann, Nathan
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208101/
https://ncbi.nlm.nih.gov/pubmed/30376893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-018-2974-z
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