Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study

BACKGROUND: Drug repurposing has been an interesting and cost-effective approach, especially for neglected diseases, such as Chagas disease. METHODS: In this work, we studied the activity of the antidepressant drug sertraline against Trypanosoma cruzi trypomastigotes and intracellular amastigotes of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Venom Anim Toxins Incl Trop Dis
Prif Awduron: Ferreira, Daiane Dias, Mesquita, Juliana Tonini, da Costa Silva, Thais Alves, Romanelli, Maiara Maria, da Gama Jaen Batista, Denise, da Silva, Cristiane França, da Gama, Aline Nefertiti Silva, Neves, Bruno Junior, Melo-Filho, Cleber Camilo, Correia Soeiro, Maria de Nazare, Andrade, Carolina Horta, Tempone, Andre Gustavo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208092/
https://ncbi.nlm.nih.gov/pubmed/30450114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40409-018-0165-8
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