Estrogen rescues heart failure through estrogen receptor Beta activation

BACKGROUND: Recently, we showed that exogenous treatment with estrogen (E2) rescues pre-existing advanced heart failure (HF) in mice. Since most of the biological actions of E2 are mediated through the classical estrogen receptors alpha (ERα) and/or beta (ERβ), and both these receptors are present i...

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Dettagli Bibliografici
Pubblicato in:Biol Sex Differ
Autori principali: Iorga, Andrea, Umar, Soban, Ruffenach, Gregoire, Aryan, Laila, Li, Jingyuan, Sharma, Salil, Motayagheni, Negar, Nadadur, Rangarajan D., Bopassa, Jean C., Eghbali, Mansoureh
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208048/
https://ncbi.nlm.nih.gov/pubmed/30376877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-018-0206-6
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