טוען...
Severe pulmonary hypertension in aging female apolipoprotein E-deficient mice is rescued by estrogen replacement therapy
BACKGROUND: Apolipoprotein E (ApoE) is a multifunctional protein, and its deficiency leads to the development of atherosclerosis in mice. Patients with pulmonary hypertension (PH) have reduced expression of ApoE in lung tissue. ApoE is known to inhibit endothelial and smooth muscle cell proliferatio...
שמור ב:
| הוצא לאור ב: | Biol Sex Differ |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5360087/ https://ncbi.nlm.nih.gov/pubmed/28344760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-017-0129-7 |
| תגים: |
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