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Nucleotide excision repair is a predictor of early relapse in pediatric acute lymphoblastic leukemia

BACKGROUND: Nucleotide Excision Repair (NER) is a major pathway of mammalian DNA repair that is associated with drug resistance and has not been well characterized in acute lymphoblastic leukemia (ALL). The objective of this study was to explore the role of NER in relapsed ALL patients. We hypothesi...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Ibrahim, Omar M., As Sobeai, Homood M., Grant, Stephen G., Latimer, Jean J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208034/
https://ncbi.nlm.nih.gov/pubmed/30376844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0422-2
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