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Nucleotide excision repair is a predictor of early relapse in pediatric acute lymphoblastic leukemia

BACKGROUND: Nucleotide Excision Repair (NER) is a major pathway of mammalian DNA repair that is associated with drug resistance and has not been well characterized in acute lymphoblastic leukemia (ALL). The objective of this study was to explore the role of NER in relapsed ALL patients. We hypothesi...

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Publicat a:BMC Med Genomics
Autors principals: Ibrahim, Omar M., As Sobeai, Homood M., Grant, Stephen G., Latimer, Jean J.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208034/
https://ncbi.nlm.nih.gov/pubmed/30376844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0422-2
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