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Palmitic Acid Downregulates Thyroglobulin (Tg), Sodium Iodide Symporter (NIS), and Thyroperoxidase (TPO) in Human Primary Thyrocytes: A Potential Mechanism by Which Lipotoxicity Affects Thyroid?

Our previous studies suggested that the thyroid might be a target organ affected by lipotoxicity, which might be partially related to the increasing prevalence of subclinical hypothyroidism. However, the underlying molecular mechanism is not yet clearly established. This study aimed to assess the ef...

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Détails bibliographiques
Publié dans:Int J Endocrinol
Auteurs principaux: Zhao, Meng, Zhang, Xiaohan, Gao, Ling, Song, Yongfeng, Xu, Chao, Yu, Chunxiao, Shao, Shanshan, Zhao, Jiajun
Format: Artigo
Langue:Inglês
Publié: Hindawi 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207890/
https://ncbi.nlm.nih.gov/pubmed/30416522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4215848
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