Repeated rectal application of a hyperosmolar lubricant is associated with microbiota shifts but does not affect PrEP drug concentrations: results from a randomized trial in men who have sex with men

INTRODUCTION: Oral pre‐exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) is highly effective in preventing HIV infection among men who have sex with men (MSM). The effects of consistent personal lubricant use in the rectum on tissue PrEP drug concentrations...

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Detalhes bibliográficos
Publicado no:J Int AIDS Soc
Main Authors: Haaland, Richard E, Fountain, Jeffrey, Hu, Yingtian, Holder, Angela, Dinh, Chuong, Hall, LaShonda, Pescatore, Nicole A, Heeke, Sheila, Hart, Clyde E, Xu, Jiahui, Hu, Yi‐Juan, Kelley, Colleen F
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207839/
https://ncbi.nlm.nih.gov/pubmed/30378274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jia2.25199
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