Repeated rectal application of a hyperosmolar lubricant is associated with microbiota shifts but does not affect PrEP drug concentrations: results from a randomized trial in men who have sex with men

INTRODUCTION: Oral pre‐exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) is highly effective in preventing HIV infection among men who have sex with men (MSM). The effects of consistent personal lubricant use in the rectum on tissue PrEP drug concentrations...

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Dades bibliogràfiques
Publicat a:J Int AIDS Soc
Autors principals: Haaland, Richard E, Fountain, Jeffrey, Hu, Yingtian, Holder, Angela, Dinh, Chuong, Hall, LaShonda, Pescatore, Nicole A, Heeke, Sheila, Hart, Clyde E, Xu, Jiahui, Hu, Yi‐Juan, Kelley, Colleen F
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207839/
https://ncbi.nlm.nih.gov/pubmed/30378274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jia2.25199
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