Network integration of multi-tumour omics data suggests novel targeting strategies

We characterize different tumour types in search for multi-tumour drug targets, in particular aiming for drug repurposing and novel drug combinations. Starting from 11 tumour types from The Cancer Genome Atlas, we obtain three clusters based on transcriptomic correlation profiles. A network-based an...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: do Valle, Ítalo Faria, Menichetti, Giulia, Simonetti, Giorgia, Bruno, Samantha, Zironi, Isabella, Durso, Danielle Fernandes, Mombach, José C. M., Martinelli, Giovanni, Castellani, Gastone, Remondini, Daniel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207774/
https://ncbi.nlm.nih.gov/pubmed/30375513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06992-7
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