Network integration of multi-tumour omics data suggests novel targeting strategies

We characterize different tumour types in search for multi-tumour drug targets, in particular aiming for drug repurposing and novel drug combinations. Starting from 11 tumour types from The Cancer Genome Atlas, we obtain three clusters based on transcriptomic correlation profiles. A network-based an...

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Bibliographic Details
Published in:Nat Commun
Main Authors: do Valle, Ítalo Faria, Menichetti, Giulia, Simonetti, Giorgia, Bruno, Samantha, Zironi, Isabella, Durso, Danielle Fernandes, Mombach, José C. M., Martinelli, Giovanni, Castellani, Gastone, Remondini, Daniel
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207774/
https://ncbi.nlm.nih.gov/pubmed/30375513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06992-7
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