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Adrenal hormones mediate disease tolerance in malaria

Malaria reduces host fitness and survival by pathogen-mediated damage and inflammation. Disease tolerance mechanisms counter these negative effects without decreasing pathogen load. Here, we demonstrate that in four different mouse models of malaria, adrenal hormones confer disease tolerance and pro...

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Udgivet i:Nat Commun
Main Authors: Vandermosten, Leen, Pham, Thao-Thy, Knoops, Sofie, De Geest, Charlotte, Lays, Natacha, Van der Molen, Kristof, Kenyon, Christopher J., Verma, Manu, Chapman, Karen E., Schuit, Frans, De Bosscher, Karolien, Opdenakker, Ghislain, Van den Steen, Philippe E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207723/
https://ncbi.nlm.nih.gov/pubmed/30375380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06986-5
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