Adrenal hormones mediate disease tolerance in malaria

Malaria reduces host fitness and survival by pathogen-mediated damage and inflammation. Disease tolerance mechanisms counter these negative effects without decreasing pathogen load. Here, we demonstrate that in four different mouse models of malaria, adrenal hormones confer disease tolerance and pro...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Vandermosten, Leen, Pham, Thao-Thy, Knoops, Sofie, De Geest, Charlotte, Lays, Natacha, Van der Molen, Kristof, Kenyon, Christopher J., Verma, Manu, Chapman, Karen E., Schuit, Frans, De Bosscher, Karolien, Opdenakker, Ghislain, Van den Steen, Philippe E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207723/
https://ncbi.nlm.nih.gov/pubmed/30375380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06986-5
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