Standardized phytotherapic extracts rescue anomalous locomotion and electrophysiological responses of TDP-43 Drosophila melanogaster model of ALS

Findings from studies using animal models expressing amyotrophic lateral sclerosis (ALS) mutations in RNA-binding proteins, such as Transactive Response DNA-binding protein-43 (TDP-43), indicate that this protein, which is involved in multiple functions, including transcriptional regulation and pre-...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Maccioni, Riccardo, Setzu, Maria Dolores, Talani, Giuseppe, Solari, Paolo, Kasture, Ameya, Sucic, Sonja, Porru, Simona, Muroni, Patrizia, Sanna, Enrico, Kasture, Sanjay, Acquas, Elio, Liscia, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207707/
https://ncbi.nlm.nih.gov/pubmed/30375462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34452-1
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