Identification of the minimal bacterial 2’-deoxy-7-amido-7-deazaguanine synthesis machinery

The 7-deazapurine derivatives, 2’-deoxy-7-cyano-7-deazaguanosine (dPreQ(0)) and 2’-deoxy-7-amido-7-deazaguanosine (dADG) are recently-discovered DNA modifications encoded by the dpd cluster found in a diverse set of bacteria. Here we identify the genes required for formation of dPreQ(0) and dADG in...

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發表在:Mol Microbiol
Main Authors: Yuan, Yifeng, Hutinet, Geoffrey, Valera, Jacqueline Gamboa, Hu, Jennifer, Hillebrand, Roman, Gustafson, Andrew, Iwata-Reuyl, Dirk, Dedon, Peter C., de Crécy-Lagard, Valérie
格式: Artigo
語言:Inglês
出版: 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207457/
https://ncbi.nlm.nih.gov/pubmed/30159947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14113
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