Compensatory evolution drives multidrug-resistant tuberculosis in Central Asia

Bacterial factors favoring the unprecedented multidrug-resistant tuberculosis (MDR-TB) epidemic in the former Soviet Union remain unclear. We utilized whole genome sequencing and Bayesian statistics to analyze the evolutionary history, temporal emergence of resistance and transmission networks of MD...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Merker, Matthias, Barbier, Maxime, Cox, Helen, Rasigade, Jean-Philippe, Feuerriegel, Silke, Kohl, Thomas Andreas, Diel, Roland, Borrell, Sonia, Gagneux, Sebastien, Nikolayevskyy, Vladyslav, Andres, Sönke, Nübel, Ulrich, Supply, Philip, Wirth, Thierry, Niemann, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2018
Fag:
Evolutionary Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207422/
https://ncbi.nlm.nih.gov/pubmed/30373719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38200
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