CD40L coding oncolytic adenovirus allows long-term survival of humanized mice receiving dendritic cell therapy

Dendritic cells (DCs) are crucial players in promoting immune responses. Logically, adoptive DC therapy is a promising approach in cancer immunotherapy. One of the major obstacles in cancer immunotherapy in general is the immunosuppressive tumor microenvironment, which hampers the maturation and act...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Zafar, Sadia, Sorsa, Suvi, Siurala, Mikko, Hemminki, Otto, Havunen, Riikka, Cervera-Carrascon, Victor, Santos, João Manuel, Wang, Hongjie, Lieber, Andre, De Gruijl, Tanja, Kanerva, Anna, Hemminki, Akseli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207416/
https://ncbi.nlm.nih.gov/pubmed/30386680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1490856
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