Gold nanorods/siRNA complex administration for knockdown of PARP-1: a potential treatment for perinatal asphyxia

BACKGROUND: Perinatal asphyxia interferes with neonatal development, resulting in long-term deficits associated with systemic and neurological diseases. Despite the important role of poly (ADP-ribose) polymerase 1 (PARP-1) in the regulation of gene expression and DNA repair, overactivation of PARP-1...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Vio, Valentina, Riveros, Ana L, Tapia-Bustos, Andrea, Lespay-Rebolledo, Carolyne, Perez-Lobos, Ronald, Muñoz, Luis, Pismante, Paola, Morales, Paola, Araya, Eyleen, Hassan, Natalia, Herrera-Marschitz, Mario, Kogan, Marcelo J
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207385/
https://ncbi.nlm.nih.gov/pubmed/30498346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S175076
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