An unusually high substitution rate in transplant-associated BK polyomavirus in vivo is further concentrated in HLA-C-bound viral peptides

Infection with human BK polyomavirus, a small double-stranded DNA virus, potentially results in severe complications in immunocompromised patients. Here, we describe the in vivo variability and evolution of the BK polyomavirus by deep sequencing. Our data reveal the highest genomic evolutionary rate...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Domingo-Calap, Pilar, Schubert, Benjamin, Joly, Mélanie, Solis, Morgane, Untrau, Meiggie, Carapito, Raphael, Georgel, Philippe, Caillard, Sophie, Fafi-Kremer, Samira, Paul, Nicodème, Kohlbacher, Oliver, González-Candelas, Fernando, Bahram, Seiamak
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207329/
https://ncbi.nlm.nih.gov/pubmed/30335851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007368
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados