Massive NGS data analysis reveals hundreds of potential novel gene fusions in human cell lines

BACKGROUND: Gene fusions derive from chromosomal rearrangements. The resulting chimeric transcripts are often endowed with oncogenic potential. Furthermore, they serve as diagnostic tools for the clinical classification of cancer subgroups with different prognosis and, in some cases, they can provid...

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Bibliografische gegevens
Gepubliceerd in:Gigascience
Hoofdauteurs: Gioiosa, Silvia, Bolis, Marco, Flati, Tiziano, Massini, Annalisa, Garattini, Enrico, Chillemi, Giovanni, Fratelli, Maddalena, Castrignanò, Tiziana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2018
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Data Note
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207142/
https://ncbi.nlm.nih.gov/pubmed/29860514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giy062
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