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Massive NGS data analysis reveals hundreds of potential novel gene fusions in human cell lines

BACKGROUND: Gene fusions derive from chromosomal rearrangements. The resulting chimeric transcripts are often endowed with oncogenic potential. Furthermore, they serve as diagnostic tools for the clinical classification of cancer subgroups with different prognosis and, in some cases, they can provid...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Gigascience
Asıl Yazarlar: Gioiosa, Silvia, Bolis, Marco, Flati, Tiziano, Massini, Annalisa, Garattini, Enrico, Chillemi, Giovanni, Fratelli, Maddalena, Castrignanò, Tiziana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207142/
https://ncbi.nlm.nih.gov/pubmed/29860514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giy062
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