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Massive NGS data analysis reveals hundreds of potential novel gene fusions in human cell lines

BACKGROUND: Gene fusions derive from chromosomal rearrangements. The resulting chimeric transcripts are often endowed with oncogenic potential. Furthermore, they serve as diagnostic tools for the clinical classification of cancer subgroups with different prognosis and, in some cases, they can provid...

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Detalhes bibliográficos
Publicado no:Gigascience
Main Authors: Gioiosa, Silvia, Bolis, Marco, Flati, Tiziano, Massini, Annalisa, Garattini, Enrico, Chillemi, Giovanni, Fratelli, Maddalena, Castrignanò, Tiziana
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207142/
https://ncbi.nlm.nih.gov/pubmed/29860514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giy062
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