NOX4 and Poldip2 induce F-actin oxidation and promote its interaction with vinculin during integrin-mediated cell adhesion

OBJECTIVE: Actin cytoskeleton assembly and organization, as a result of focal adhesion formation during cell adhesion, are dependent upon reactive oxygen species (ROS) and the cellular redox environment. Polymerase delta interacting protein 2 (Poldip2), a novel regulator of NADPH oxidase 4 (NOX4), p...

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Veröffentlicht in:Arterioscler Thromb Vasc Biol
Hauptverfasser: Vukelic, Sasa, Xu, Qian, Seidel-Rogol, Bonnie, Faidley, Elizabeth A., Dikalova, Anna E., Hilenski, Lula L., Jorde, Ulrich, Poole, Leslie B., Lassègue, Bernard, Zhang, Guogang, Griendling, Kathy K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206888/
https://ncbi.nlm.nih.gov/pubmed/30354218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311668
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