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Sirtuins and NAD(+) in the Development and Treatment of Metabolic and Cardiovascular Diseases

The sirtuin family of nicotinamide adenine dinucleotide (NAD(+))-dependent deacylases (SIRT1–7) are thought to be responsible, in large part, for the cardiometabolic benefits of lean diets and exercise and when upregulated can delay key aspects of aging. SIRT1, for example, protects against a declin...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Kane, Alice E., Sinclair, David A
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206880/
https://ncbi.nlm.nih.gov/pubmed/30355082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.312498
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