Epigenetics of Delirium and Aging: Potential Role of DNA Methylation Change on Cytokine Genes in Glia and Blood Along With Aging

Background: Delirium in elderly patients is common and dangerous. Major risk factors include aging and exogenous insults, such as infection or surgery. In animal models, aging enhances pro-inflammatory cytokine release from microglia in response to exogenous insults. The epigenetic mechanism DNA met...

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Dades bibliogràfiques
Publicat a:Front Aging Neurosci
Autors principals: Shinozaki, Gen, Braun, Patricia R., Hing, Benjamin W. Q., Ratanatharathorn, Andrew, Klisares, Mason J., Duncan, Gabrielle N., Jellison, Sydney S., Heinzman, Jonathan T., Nagahama, Yasunori, Close, Liesl, Sabbagh, Sayeh, Dlouhy, Brian J., Howard, Matthew A., Kawasaki, Hiroto, Cho, Hyunkeun R.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206747/
https://ncbi.nlm.nih.gov/pubmed/30405391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00311
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