Idiopathic male infertility is strongly associated with aberrant DNA methylation of imprinted loci in sperm: a case-control study

BACKGROUND: Male infertility is a complex disease caused by a combination of genetic, environmental, and lifestyle factors. Abnormal epigenetic programming has been proposed as a possible mechanism compromising male fertility. Recent studies suggest that aberrant imprinting in spermatozoa in a subse...

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Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Tang, Qiuqin, Pan, Feng, Yang, Jing, Fu, Ziqiang, Lu, Yiwen, Wu, Xian, Han, Xiumei, Chen, Minjian, Lu, Chuncheng, Xia, Yankai, Wang, Xinru, Wu, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206675/
https://ncbi.nlm.nih.gov/pubmed/30373665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0568-y
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