Synthesis and Evaluation of Baylis-Hillman Reaction Derived Imidazole and Triazole Cinnamates as Antifungal Agents

Allylic acetates derived from Baylis-Hillman reaction undergo efficient nucleophilic isomerization with imidazoles and triazoles to provide imidazolylmethyl and triazolylmethyl cinnamates stereoselectively. Antifungal evaluation of these derivatives against Cryptococcus neoformans exhibits good mini...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int J Med Chem
Main Authors: Nelson, Grady L., Williams, Michael J., Jonnalagadda, Shirisha, Alam, Mohammad A., Mereddy, Gautam, Johnson, Joseph L., Jonnalagadda, Sravan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206569/
https://ncbi.nlm.nih.gov/pubmed/30410798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/5758076
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados