Kaposi's Sarcoma-Associated Herpesvirus Deregulates Host Cellular Replication during Lytic Reactivation by Disrupting the MCM Complex through ORF59

Minichromosome maintenance proteins (MCMs) play an important role in DNA replication by binding to the origins as helicase and recruiting polymerases for DNA synthesis. During the S phase, MCM complex is loaded to limit DNA replication once per cell cycle. We identified MCMs as ORF59 binding partner...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Strahan, Roxanne, Dabral, Prerna, Dingman, Kammi, Stadler, Christian, Hiura, Kayla, Verma, Subhash C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206491/
https://ncbi.nlm.nih.gov/pubmed/30158293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00739-18
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker