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Human Immunodeficiency Virus Type 1 gp120 and Tat Induce Mitochondrial Fragmentation and Incomplete Mitophagy in Human Neurons

HIV enters the central nervous system (CNS) during the early stages of infection and can cause neurological dysfunction, including neurodegeneration and neurocognitive impairment. The specific autophagy responsible for removal of damaged mitochondria (mitophagy) and mitochondrial dynamics constitute...

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Bibliographic Details
Published in:J Virol
Main Authors: Teodorof-Diedrich, Carmen, Spector, Stephen A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206485/
https://ncbi.nlm.nih.gov/pubmed/30158296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00993-18
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