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Human Immunodeficiency Virus Type 1 gp120 and Tat Induce Mitochondrial Fragmentation and Incomplete Mitophagy in Human Neurons

HIV enters the central nervous system (CNS) during the early stages of infection and can cause neurological dysfunction, including neurodegeneration and neurocognitive impairment. The specific autophagy responsible for removal of damaged mitochondria (mitophagy) and mitochondrial dynamics constitute...

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Pubblicato in:J Virol
Autori principali: Teodorof-Diedrich, Carmen, Spector, Stephen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206485/
https://ncbi.nlm.nih.gov/pubmed/30158296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00993-18
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