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Histopathological and functional changes in a single-dose model of combretastatin A4 disodium phosphate-induced myocardial damage in rats

Cardiotoxicity is a concern in the development of microtubule-disassembling agents (MDAs) as vascular-disrupting agents of tumors. This study investigated cardiotoxicity in rats induced by a single-dose of combretastatin A4 disodium phosphate (CA4DP), an MDA and discussed the use of this rat model i...

詳細記述

保存先:
書誌詳細
出版年:J Toxicol Pathol
主要な著者: Tochinai, Ryota, Komatsu, Kayoko, Murakami, Junta, Nagata, Yuriko, Ando, Minoru, Hata, Chie, Suzuki, Tomo, Kado, Shoichi, Kobayashi, Toshihide, Kuwahara, Masayoshi
フォーマット: Artigo
言語:Inglês
出版事項: Japanese Society of Toxicologic Pathology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206283/
https://ncbi.nlm.nih.gov/pubmed/30393435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2018-0023
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