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Cardiotoxic Changes of Colchicine Intoxication in Rats: Electrocardiographic, Histopathological and Blood Chemical Analysis

The microtubule inhibitor colchicine is cardiotoxic and is suggested to impair impulse formation and conduction. However, little is known about the electrocardiographic (ECG) changes induced by colchicine in experimental animals and the detailed pathogenesis of its cardiotoxicity. Therefore, we anal...

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Bibliografiske detaljer
Main Authors: Tochinai, Ryota, Suzuki, Katsuya, Nagata, Yuriko, Ando, Minoru, Hata, Chie, Komatsu, Kayoko, Suzuki, Tomo, Uchida, Kazumi, Kado, Shoichi, Kaneko, Kimiyuki, Kuwahara, Masayoshi
Format: Artigo
Sprog:Inglês
Udgivet: Japanese Society of Toxicologic Pathology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217234/
https://ncbi.nlm.nih.gov/pubmed/25378807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2014-0013
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