Phage-Borne Depolymerases Decrease Klebsiella pneumoniae Resistance to Innate Defense Mechanisms

Klebsiella pneumoniae produces capsular polysaccharides that are a crucial virulence factor protecting bacteria against innate response mechanisms of the infected host. Simultaneously, those capsules are targeted by specific bacteriophages equipped with virion-associated depolymerases able to recogn...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Majkowska-Skrobek, Grazyna, Latka, Agnieszka, Berisio, Rita, Squeglia, Flavia, Maciejewska, Barbara, Briers, Yves, Drulis-Kawa, Zuzanna
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205948/
https://ncbi.nlm.nih.gov/pubmed/30405575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.02517
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