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Capsule-Targeting Depolymerase, Derived from Klebsiella KP36 Phage, as a Tool for the Development of Anti-Virulent Strategy

The rise of antibiotic-resistant Klebsiella pneumoniae, a leading nosocomial pathogen, prompts the need for alternative therapies. We have identified and characterized a novel depolymerase enzyme encoded by Klebsiella phage KP36 (depoKP36), from the Siphoviridae family. To gain insights into the cat...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Majkowska-Skrobek, Grażyna, Łątka, Agnieszka, Berisio, Rita, Maciejewska, Barbara, Squeglia, Flavia, Romano, Maria, Lavigne, Rob, Struve, Carsten, Drulis-Kawa, Zuzanna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192385/
https://ncbi.nlm.nih.gov/pubmed/27916936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8120324
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