Evidence of response to pembrolizumab in a patient with Lynch syndrome-related metastatic colon cancer

Patients with Lynch Syndrome (LS) are at high risk of developing colorectal cancer at an early age. Germline mutations in DNA mismatch repair genes and microsatellite instability are clear signatures of this autosomal dominant disorder. Here, we report the clinical history of a 38-year-old patient w...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Salman, Pamela, Panay, Sergio, Fernández, René, Mahave, Mauricio, Soza-Ried, Cristian
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2018
Subjects:
Case Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205820/
https://ncbi.nlm.nih.gov/pubmed/30425520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S167645
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