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Evidence of response to pembrolizumab in a patient with Lynch syndrome-related metastatic colon cancer

Patients with Lynch Syndrome (LS) are at high risk of developing colorectal cancer at an early age. Germline mutations in DNA mismatch repair genes and microsatellite instability are clear signatures of this autosomal dominant disorder. Here, we report the clinical history of a 38-year-old patient w...

詳細記述

保存先:
書誌詳細
出版年:Onco Targets Ther
主要な著者: Salman, Pamela, Panay, Sergio, Fernández, René, Mahave, Mauricio, Soza-Ried, Cristian
フォーマット: Artigo
言語:Inglês
出版事項: Dove Medical Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205820/
https://ncbi.nlm.nih.gov/pubmed/30425520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S167645
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