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Evidence of response to pembrolizumab in a patient with Lynch syndrome-related metastatic colon cancer
Patients with Lynch Syndrome (LS) are at high risk of developing colorectal cancer at an early age. Germline mutations in DNA mismatch repair genes and microsatellite instability are clear signatures of this autosomal dominant disorder. Here, we report the clinical history of a 38-year-old patient w...
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| Publicado no: | Onco Targets Ther |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6205820/ https://ncbi.nlm.nih.gov/pubmed/30425520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S167645 |
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