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Evidence of response to pembrolizumab in a patient with Lynch syndrome-related metastatic colon cancer
Patients with Lynch Syndrome (LS) are at high risk of developing colorectal cancer at an early age. Germline mutations in DNA mismatch repair genes and microsatellite instability are clear signatures of this autosomal dominant disorder. Here, we report the clinical history of a 38-year-old patient w...
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| 出版年: | Onco Targets Ther |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove Medical Press
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6205820/ https://ncbi.nlm.nih.gov/pubmed/30425520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S167645 |
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