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Focal Cerebral Ischemia and Reperfusion Induce Brain Injury through α2δ−1–Bound NMDA Receptors
BACKGROUND AND PURPOSE: Glutamate N-methyl-D-aspartate receptors (NMDARs) play a major role in the initiation of ischemic brain damage. However, NMDAR antagonists have no protective effects in stroke patients, possibly because they impair physiological functions of NMDARs. α2δ−1 (encoded by Cacna2d1...
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| Publicado no: | Stroke |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6205748/ https://ncbi.nlm.nih.gov/pubmed/30355118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.118.022330 |
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