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Yin-and-yang bifurcation of opioidergic circuits for descending analgesia at the midbrain of the mouse
In the descending analgesia pathway, opioids are known to disinhibit the projections from the periaqueductal gray (PAG) to the rostral ventromedial medulla (RVM), leading to suppression of pain signals at the spinal cord level. The locus coeruleus (LC) has been proposed to engage in the descending p...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6205495/ https://ncbi.nlm.nih.gov/pubmed/30297409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806082115 |
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