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Yin-and-yang bifurcation of opioidergic circuits for descending analgesia at the midbrain of the mouse

In the descending analgesia pathway, opioids are known to disinhibit the projections from the periaqueductal gray (PAG) to the rostral ventromedial medulla (RVM), leading to suppression of pain signals at the spinal cord level. The locus coeruleus (LC) has been proposed to engage in the descending p...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Kim, Jong-Hyun, Gangadharan, Gireesh, Byun, Junweon, Choi, Eui-Ju, Lee, C. Justin, Shin, Hee-Sup
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205495/
https://ncbi.nlm.nih.gov/pubmed/30297409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806082115
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